Category Archives: Airway

Canadian Neighbor Pharmacy: Chronic Airflow Limitation

pneumoconiosesWhile the classic diseases of dusty occupations, in particular the pneumoconioses, have not yet disappeared, they may be on the decline. In contrast, mortality rates due to the chronic nonmalignant pulmonary conditions including those characterized by airflow limitation are increasing in the industrialized countries of the world, and they are also responsible for high rates of morbidity and extended periods of disablement. Like other chronic lifestyle diseases, these are also almost certainly multifactorial in etiology, involving host factors as well as environmental factors. Among the latter, cigarette smoking is the most important. As chronic disease epidemiology has improved, it has become possible to investigate the role of environmental factors other than the cigarette, and there is now increasing evidence that exposures to other airborne pollutants also play a role, including those to which men and women are exposed at work. The purpose of this review is (1) to set in context some of the recently published information on the role of work in dusty occupations; (2) to assess its role visavis that of cigarettes; and (3) to reassess the evidence for causality. It addresses the question: can the exposures which men and women encounter in the course of their daily work lead to chronic airflow limitation sufficiently severe to disable them?

Canadian Health and Care Mall: Disscusion of Measurement of Tidal Breath by Determination of Chest Wall Volume Displacement in Patients with Airflow Obstruction

The spirometer with mouthpieceThe spirometer with mouthpiece and noseclips (MPC/NC) provides a simple, precise technology for the measurement of maximal pulmonary volumes and flow rates. The MPC/NC provides an artificial milieu for the measurement of resting ventilation (Ve), however. As such, MPC/NC stimulate change in the breathing pattern, for Vt measured by spirometer exceeds that measured noninvasively by 15 percent in normal subjects. One might expect that determination of Vt in disease states, and most important to the clinician, the determination of change in Vt induced by therapy, will be affected by MPC/NC as well.