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Category: Clinical presentation

Clinical presentation of patients with aseptic meningitis: Discussion (part 3)

Adult patients who received antibiotics were likely to have relatively low glucose levels, a sign associated with bacterial meningitis. Surprisingly, one-fourth of patients who were empirically treated remained on the anti-infectives after the positive PCR test result was available. This Read More

Clinical presentation of patients with aseptic meningitis: Discussion (part 1)

There was a considerable overlap in the clinical and laboratory features of patients with and without EV meningitis. Patients with EV meningitis were frequently admitted and were treated empirically with antibiotics and acyclovir. EV meningitis was more common in younger Read More

Clinical presentation of patients with aseptic meningitis: Results — The decision to admit (part 3)

The overall length of stay in hospital was shorter in the group whose CSF was positive for EV. The EV-positive group had a mean stay of 5.44±1.07 days (n=27), significantly fewer days than the EV-negative group (14.31±2.36 days [n=70], P=0.024). Read More

Clinical presentation of patients with aseptic meningitis: Results — The decision to admit (part 2)

CSF properties, such as glucose or protein concentration, WBC count, or cell differential did not predict which patients would be admitted to the hospital (Table 3). Glucose levels were within the normal range (2.2 mmol/L to 3.9 mmol/L) in all Read More

Clinical presentation of patients with aseptic meningitis: Results — The decision to admit (part 1)

In all, 83.6% of patients were admitted for treatment or observation (n=116, one patient left against medical advice). A linear regression analysis was conducted on the following variables to determine the most important factors in patient admission: sex, age older Read More

Clinical presentation of patients with aseptic meningitis: Results — Initial presentation (part 2)

EV-positive patients were less likely than EV-negative patients to report seizure (2.9% versus 18.1%, P=0.037) or to demonstrate focal neurological findings (6.3% versus 36.1%, P=0.001). However, the average Glasgow Coma Scores (GCS), where recorded, were near normal (GCS=15) and were Read More

Clinical presentation of patients with aseptic meningitis: Results — Initial presentation (part 1)

The records of 34 EV-positive patients (nine adults, 25 children) and 83 control patients (57 adults, 26 children) were consulted for differences in signs, symptoms and characteristics using Fisher’s exact test (Table 1). The EV-positive group was significantly younger (mean Read More

Clinical presentation of patients with aseptic meningitis: Results — Anti-infective use

Further analysis (linear regression using the same characteristics as above) of the empirically treated group demonstrated that age older than 16 years was a determinant in the provision of acyclovir, accounting for 22.6% (n=38) of the variability between the administered Read More

Clinical presentation of patients with aseptic meningitis: Methods

Subsequent to appropriate ethics approval from both institutions, patients seen at Capital District Health Authority (CDHA) (Halifax, Nova Scotia) hospitals or the Izaak Walton Killam (IWK) Hospital (Halifax, Nova Scotia) whose CSF samples were tested for the presence of enterovirus Read More

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