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Category: Community-acquired pneumonia

Inpatient care of community-acquired pneumonia: DISCUSSION (5)

Limitations of the PSI may be related to either intrinsically poor accuracy or inadequate transportability. Given the excellent performance of the model in the validation set of Fine et al , we suspect that the PSI is not intrinsically inaccurate, Read More

Inpatient care of community-acquired pneumonia: DISCUSSION (4)

The association that we observed between certain antibiotic combinations and mortality may relate to effects of the antimicrobials themselves (inferior antibacterial effect or increased toxicity) or the presence of an unknown confounder, a particular problem in any study that is Read More

Inpatient care of community-acquired pneumonia: DISCUSSION (3)

There are several noteworthy observations regarding the use of specific antibiotics — buy ampicillin. The choice of antibiotic therapy was associated with illness severity. There was progressively increasing severity, measured by the PSI, in cases treated with macrolide monotherapy, cephalosporin Read More

Inpatient care of community-acquired pneumonia: DISCUSSION (2)

We were unable to detect an association between guideline adherence and mortality or LOS. The apparent lack of association could be due to a true lack of benefit from guideline adherence, inadequate power to detect a difference or a systematic Read More

Inpatient care of community-acquired pneumonia: DISCUSSION (1)

We consider our experience with the inpatient treatment of CAP to be generalizable to similar contemporary populations in other Canadian centres. The cohort was composed of elderly patients (mean age 78 years) with a high risk of mortality (mean PSI Read More

Inpatient care of community-acquired pneumonia: RESULTS (2)

Analysis by empirical antibiotic regimen The most commonly-selected antibiotic regimens are shown in Figure 2. Quinolone monotherapy (levofloxacin in 98%) and cephalosporin monotherapy (cefuroxime in over 90%) were the two most common regimens in the recent and early cohorts, respectively. Read More

Inpatient care of community-acquired pneumonia: RESULTS (1)

Of the 2324 potentially eligible cases, approximately 70% from each era were reviewed (Figure 1). Of the 1682 (72%) potentially eligible cases reviewed, 698 eligible cases were identified and reviewed in full. Of the 984 ineligible cases, 416 (42%) were Read More

Inpatient care of community-acquired pneumonia: PATIENTS AND METHODS (3)

Statistical analysis Baseline characteristics and outcomes are described as one large group and divided by era and guideline adherence. Continuous data are expressed as mean (± SD) for normal distributions or median (plus quartiles) and compared with t tests or Read More

Inpatient care of community-acquired pneumonia: PATIENTS AND METHODS (2)

All three sites have general internal medicine (GIM) clinical teaching units into which patients with CAP are generally admitted and managed. The source of referrals is almost exclusively from the emergency department (ED), to which patients either self-refer or are Read More

Inpatient care of community-acquired pneumonia: PATIENTS AND METHODS (1)

Patients and study site Charts of potential cases were identified retrospectively by International Coding of Diagnosis (Ninth Revision) classification, including codes for pneumonia and potentially overlapping diagnostic codes, including chronic bronchitis, emphysema and asthma — buy flovent inhaler. A stratified, Read More

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