Loading

wait a moment

Feasibility of Routine Pulmonary Arterial Impedance Measurements in Pulmonary Hypertension: Clinical Implications

Thus, it may be that proximal pulmonary arterial changes leading to increased Zc and RF are predominantly the passive consequences of increased mean distending pressure, and that “fixed” proximal pulmonary arterial remodeling plays a minor role in determining RV hydraulic Read More

Feasibility of Routine Pulmonary Arterial Impedance Measurements in Pulmonary Hypertension: Effects of Pharmacologic Interventions

However, PVR is known to be insufficient for the evaluation of all the forces that oppose RV ejection, which result from a dynamic interplay among resistance, elastance, and wave reflection. This information is contained in Ppa and flow waves, and Read More

Feasibility of Routine Pulmonary Arterial Impedance Measurements in Pulmonary Hypertension: Pharmacologic Interventions

Inhaled NO therapy decreased Ppa and PVR, while Q, HR, and Psa remained unaffected. Z0, Z1; and Zc decreased, while Fmin, phase indexes, and RF were unchanged (Table 2). Epoprostenol therapy decreased PVR and Psa, increased Q, while HR remained Read More

Feasibility of Routine Pulmonary Arterial Impedance Measurements in Pulmonary Hypertension: Statistical Analysis

The dose of NO had been selected on the basis of findings from previous reports that 10 to 20 ppm allows the maximum possible pulmonary vasodilation in PAH patients. NO was supplied from a pure NO source tank (Oxhydrique; Machelen, Read More

Feasibility of Routine Pulmonary Arterial Impedance Measurements in Pulmonary Hypertension: Protocol

Ppa and flow signals were recorded after the pulmonary catheter was then carefully withdrawn to position its tip just above the pulmonary valve, as close as possible to the pulsed Doppler pulmonary artery flow-velocity sampling site. The signals were visually Read More

Feasibility of Routine Pulmonary Arterial Impedance Measurements in Pulmonary Hypertension: Right Heart Catheterization

Right heart catheterization was performed without premedication, with the patient lying supine and breathing room air. A balloon-tipped, flow-directed thermodilution 7F Swan-Ganz catheter (131HF7; Baxter Healthcare Corp; Irvine, CA) was inserted under local anesthesia into an internal jugular vein and Read More

Feasibility of Routine Pulmonary Arterial Impedance Measurements in Pulmonary Hypertension: Materials and Methods

There are only a few previous studies, on PVZ in PAH patients. This is to be explained by the technical difficulties of instantaneous pressure and flow measurements requiring high-fidelity, manometer-tipped catheters and flowmeters. It has been generally assumed that the Read More

Feasibility of Routine Pulmonary Arterial Impedance Measurements in Pulmonary Hypertension

Right heart catheterization with measurements of pulmonary vascular pressures and cardiac output, and the calculation of pulmonary vascular resistance (PVR) is an essential step in the diagnosis of pulmonary arterial hypertension (PAH). These hemodynamic measurements are of prognostic value, with, Read More

Identification of Spontaneous Feline Idiopathic Pulmonary Fibrosis: Summary

An abnormality in alveolar repair would also preclude the necessity of continued superimposed inflammation to drive alveolar remodeling; the lack of an essential role for inflammation in the pathogenesis has been proposed by Selman et al. The ultrastructural findings in Read More

Identification of Spontaneous Feline Idiopathic Pulmonary Fibrosis: Human disease

The distribution of myofibroblasts in feline IPF are similar to that of the human disease. While myofibroblasts are found in rodent models of pulmonary fibrosis, because of the lack of honeycombing, they lack the relationship with the metaplastic epithelium that Read More

Pages: Prev 1 2 3 4 5 6 7 8 9 10 ... 75 76 77 Next