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Prevalence and Correlates of Airway Obstruction in a Community-Based Sample of AdultsProcedures: Discussion

Prevalence and Correlates of Airway Obstruction in a Community-Based Sample of AdultsProcedures: DiscussionTable 4 presents factors that have an independent effect on airway obstruction. In addition to the adjustment for age and gender, adjustments also were made for the number of pack-years of smoking and alcohol intake. These latter two variables were included as covariates since they showed significant relationships with airway obstruction in models that included adjustments for age. Based on these adjusted models, the odds of disease were 3.2 times greater (95% confidence interval [CI], 1.7 to 6.2) in subjects who had smoked for a 20 pack-years vs those who had never smoked. There was more than a fourfold excess in the odds of disease (adjusted odds ratio [OR], 4.3; 95% CI, 2.6 to 7.0) in subjects aged a 45 years vs those who were younger. When age, number of pack-years of cigarette smoking, and alcohol intake were adjusted as continuous variables, the excess in airway obstruction was significantly observed in men vs women (adjusted OR, 1.8; 95% CI, 1.1 to 2.9). canadian neighbor pharmacy

The prevalence of airway obstruction in adults aged a 18 years was 10.3% (men, 17.0%; women, 5.6%) by ATS criteria in the Korean community of Ansan City. In separating estimation, it was 7.6% (men, 8.1%; women, 7.2%) based on European Respiratory Society criteria (FEV1/VC ratio: men, < 88% predicted; women, < 89% predicted). Unfortunately, comparisons with other studies are difficult because of differences in age, sex, and sampled characteristics. The methods and definitions of the disease characterized by the term airway obstruction are also poorly standardized.
Nevertheless, some data have suggested that the prevalence of airway obstruction in Korea is less than that in other regions of the world. In a survey of the Po Delta area (northern Italy) from 1988 to 1991, the overall prevalence of airway obstruction for subjects aged а 25 years was 40.4% by ATS criteria.
Table 4 —Independent Risk Factors Associated With Airway Obstruction

Variables AdjustedOR* 95% CI p Value*
Age, yr
18-44 1t < 0.001
a 45 4.3л 2.6-7.0
Gender
Women 1t 0.029§
Men 1.8 1.1-2.9
Pack-years
0 1t < 0.001
0.1-9.9 1.1 0.5-2.6
10.0-19.9 1.6 0.7-3.5
a 20.0 3.2л 1.7-6.2
Alcohol intake, drinks/wk
0 1t 0.637
1 -7 1.1 0.7-1.9
8-21 1.0 0.5-2.0
a 22 1.4 0.6-3.1