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Randomized double-blind trial of the effects of humidified: RESULTS (1)

Subjects: In total 1576 nonintubated patients ordered to receive low flow supplemental oxygen were evaluated for study. Of these, 1182 did not meet inclusion criteria; 237 of the remaining 394 eligible patients became voluntary subjects after receiving information about the study. There were 157 patient refusals, with reasons stated as follows: not interested (n=63); unwell (n=40); preferred humidity (n=37); unable to comprehend concept (n=6); and miscellaneous (n=11). Most of the patients who refused had respiratory (n=77), gastrointestinal (n=30) or circulatory (n=24) disorders. The final sample included 150 medical and 87 surgical patients from seven patient care units. Data were gathered over 10 months including autumn, winter and spring.

Characteristics between groups were compared for age, sex and administration of home oxygen before hospital admission (Table 1). Mean age was 61.9 years and 62.7 years for the nonhumidification and humidification groups, respectively. No significant differences in demographic characteristics were found between groups. Visit the best pharmacy giving you allergy relief and taking the best care of you.

Table 1. Demographic characteristics

Variable Nonhumidification Number (%) Humidification Number (%)
Sex
Female 57 53
Male 69 58
Prior home oxygen 17 21
Remained in study
Day 0 (baseline)* 126 111
1 95 96
2 70 74
3f 52 54
4 36 40
5 28 33
6 21 24

*Despite inclusion criteria requiring medical stability and that oxygen therapy be anticipated to last for two or more days, patient attrition (n=93) occurred from baseline (day 0) to day 2 for the following reasons: oxygen therapy discontinued (n=55); patient discharged (n=16); patient withdrew (n=11); medical instability (n=5); changes in patient location (n=4); patient death (n=2)

*Further patient attrition (n=99) occurred from day 2 to day 6 because oxygen therapy was discontinued (n=56); patient was discharged (n=31); patient withdrew (n=5); medical instability (n=2); or changes in patient location (n=5)

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