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Stage-Dependent Accumulation of Cadmium: RESULTS(3)


The 109Cd-concentrating potential of GZ, when expressed as tissue:plasma ratios, was 2:1, 7:1, and 71:1, respectively, at 1, 3, and 7 days postinjection (compare Figs. 2 and 3A). antibiotic levaquin

109Cd levels in the EO were higher than in adjacent PoM tissues. Although 109Cd levels in the vas deferens were similar to those in testicular regions with elongated spermatids (PoM), < 3% of the total radioactivity was recovered from the expressed seminal fluid (containing sperm bundles at this time of year). Compared to levels in the testis, accumulated levels of 109Cd/g were higher in kidney, liver, spleen, heart, and rectal gland and lower in skeletal muscle and brain (Fig. 3B; Table 1). The liver accounted for the highest percentage of injected dose, followed by skeletal muscle, blood, and kidney (Table 1).

Only 68% of injected dose was accounted for after 24 h, indicating excretion or the presence of tracer in tissues not measured (e.g, urine, bile, skin). Although the mean body weight of animals killed at 1 day postinjection was somewhat higher than those at Days 3 and 7 (p < 0.05), there were no significant time-related differences when extragonadal tissue concentrations, fraction of injected dose, or percentage dose recovered were compared at the three time points.