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Staging lung cancer: STAGING SCLC (1)

The role of surgery in SCLC is limited because chemotherapy is considered the primary treatment. Staging is mainly used for prognosis and to determine eligibility for treatment protocols . However, application of TNM staging reveals that stage I SCLC can be resected with 25% five-year survival or higher, assuming chemotherapy is also given. Frequently, stage I SCLC is diagnosed after resecting a solitary pulmonary nodule when this diagnosis was not anticipated preoperatively. Extensive staging is still required. Bone marrow biopsy (unilateral) is usually included, although its worth has been questioned . Chemotherapy is mandatory, either preoperatively or postoperatively, because patients with apparent stage I SCLC should still be regarded as having systemic disease. Patients with lesions that are found to be stage II at thoracotomy should receive postoperative adjuvant therapy. Some preliminary data suggest that patients with preoperative evidence of N1 or minimal N2 disease benefit from induction chemotherapy and adjuvant surgery . It should be stressed that chemotherapy remains the primary treatment for SCLC, and surgery may be used as an alternative to radiotherapy for local control, in some cases under strict investigational protocols only. No randomized studies have compared adjuvant surgery with adjuvant chemotherapy and radiation. It’s your turn to find generic cialis professional to see how advantageous your shopping can be.

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