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Tag: Follicle-Stimulating Hormone

Role and Gonadotrophic Regulation of X-Linked: DISCUSSION(6)

Previous studies from our laboratory have shown that FSH increases follicular transforming growth factor a secretion and that this theca-derived growth factor induces follicular growth in vitro. In this context, recent studies using a coculture of bovine ovarian granulosa and Read More

Role and Gonadotrophic Regulation of X-Linked: DISCUSSION(5)

Our present findings indicate that although FSH is capable of increasing follicular cell number (as indicated by increased Alamar Blue reduction and DNA content) and growth in a follicle culture system, it fails to stimulate proliferation when added to granulosa Read More

Role and Gonadotrophic Regulation of X-Linked: DISCUSSION(4)

Specifically, XIAP possesses two different caspase-inhibitory activities, which can be attributed to distinct domains within XIAP. The BIR3 of XIAP is a specific inhibitor of cas-pase-9, whereas BIR2 plus the linker region of BIR1 and BIR2 is specific for caspase-3 Read More

Role and Gonadotrophic Regulation of X-Linked: DISCUSSION(3)

Follicles infected with XIAP sense and cultured in the presence of low FSH concentration (5 ng/ml) showed a marked increase in follicular development (as evidenced by increases in DNA content and follicular volume) compared to the FSH-stimulated but LacZ-infected follicles. Read More

Role and Gonadotrophic Regulation of X-Linked: DISCUSSION(2)

Transgenic and knockout animals have been used extensively to assess the role of the gene (or genes) of interest in physiological processes. However, these approaches are often plagued with systemic complications because of overall ill health of the animals, which Read More

Role and Gonadotrophic Regulation of X-Linked: DISCUSSION(1)

The FSH is an important survival factor for preantral and antral follicular development in vivo. Whereas administration of gonadotropin induces ovarian follicular development in immature animals, gonadotropin withdrawal by anti-eCG antibody treatment resulted not only in cessation of follicular growth Read More

Role and Gonadotrophic Regulation of X-Linked: RESULTS(3)

On the other hand, follicles injected with XIAP sense and subsequently cultured in the low concentration of FSH (5 ng/ml) showed high XIAP immunointensity and less-intense TUNEL signal compared to adenoviral LacZ-in-jected follicles (Fig. 5B). Although a range in the Read More

Role and Gonadotrophic Regulation of X-Linked: RESULTS(2)

FSH Increases XIAP Expression in Cultured Ovarian Follicles To determine if XIAP expression is regulated by the gonadotropin during follicular development and atresia in vitro, changes in XIAP content and apoptosis in sections of cultured follicles were examined by IHC Read More

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