Tag Archives: Translocation (Part 3)

Rat Testis Motor Proteins Associated with Spermatid Translocation (Dynein) and Spermatid Flagella (Kinesin-II)(1)

Spermatid Flagella (Kinesin-II)(1)

Numerous studies have reported the presence of dynein-and kinesin-like motor proteins in the testis. Using an antibody raised against bovine brain MAP1C (microtubule-associated protein 1C), Yoshida and coworkers localized cytoplasmic dynein, in the testis, to spermatid manchettes (microtubule-rich organelles associated with the posterior aspect of the nucleus). They also noted a moderately intense staining of Sertoli cells. In a separate study, and using a different antibody, dynein was observed not only in spermatid manchettes and in Sertoli cell cytoplasm but also in ectoplasmic specializations associated with spermatids during early stages of differentiation. Kinesin has been detected in the spermatid manchette and the Sertoli cell trans-Golgi network. buy cipro

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